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Pumpkin seed oil-loaded niosomes for topical application: 5α-reductase inhibitory, anti-inflammatory, and in vivo anti-hair loss effects.

PMID:  Pharmaceuticals (Basel). 2022 Jul 27 ;15(8). Epub 2022 Jul 27. PMID: 36015077 Abstract Title:  Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects. Abstract:  Pumpkin seed oil (PSO)-loaded niosomes were prepared from Tween 20 and cholesterol by ethanol injection. Confocal microscopy showed better skin permeation and hair […]

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7 Evidence-Based Activities for Parkinson’s Disease

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. © Copyright 2008-2022 […]

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Astaxanthin attenuates osteoarthritis progression.

PMID:  Chem Biol Interact. 2022 Sep 6:110148. Epub 2022 Sep 6. PMID: 36084724 Abstract Title:  Astaxanthin attenuates osteoarthritis progression via inhibiting ferroptosis and regulating mitochondrial function in chondrocytes. Abstract:  Ferroptosis is a novel form of regulated cell death that has a close association with mitochondrial dysfunction and is characterized by iron overload, the accumulation of […]

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Accelerated bone regeneration by an astaxanthin-modified antioxidant aerogel.

PMID:  ACS Biomater Sci Eng. 2022 Sep 8. Epub 2022 Sep 8. PMID: 36073984 Abstract Title:  Accelerated Bone Regeneration by an Astaxanthin-Modified Antioxidant Aerogel through Relieving Oxidative Stress via the NRF2 Signaling Pathway. Abstract:  Bone regeneration of critical-sized bone defects (CSBDs) with biomimetic collagen-based aerogels remains a significant challenge due to the oxidative stress on […]

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Astragaloside IV protects against ischemia/reperfusion (I/R)-induced kidney injury based on the Keap1-Nrf2/ARE signaling pathway.

PMID:  Transl Androl Urol. 2022 Aug ;11(8):1177-1188. PMID: 36092836 Abstract Title:  Astragaloside IV protects against ischemia/reperfusion (I/R)-induced kidney injury based on the Keap1-Nrf2/ARE signaling pathway. Abstract:  Background: This study sought to investigate the protective effects of Astragaloside IV (AS-IV) on ischemia-reperfusion (I/R) renal injury based on the keap1-Nrf2/ARE signaling pathway.Methods: A total of 36 male […]

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Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway.

PMID:  Front Pharmacol. 2022 ;13:924826. Epub 2022 Aug 19. PMID: 36059982 Abstract Title:  Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhageNrf2/HO-1 signaling pathway. Abstract:  Subarachnoid hemorrhage (SAH) is a severe type of stroke featuring exceptionally high rate of morbidity and mortality due to the lack of effective management. Ferroptosis can be defined as a novel iron-dependent […]

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Accelerating effect of Cucurbita pepo L. fruit extract on excisional wound healing.

PMID:  Nutrients. 2022 Aug 15 ;14(16). Epub 2022 Aug 15. PMID: 36014842 Abstract Title:  Accelerating Effect ofL. Fruit Extract on Excisional Wound Healing in Depressed Rats Is Mediated through Its Anti-Inflammatory and Antioxidant Effects. Abstract:  BACKGROUND: Chronic stress can hinder wound healing as it suppresses both the cellular and innate immune responses.OBJECTIVES: The study aims […]

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In vitro role of pumpkin parts as pharma-Foods: antihyperglycemic and antihyperlipidemic activities.

PMID:  Int J Food Sci. 2022 ;2022:4804408. Epub 2022 Aug 2. PMID: 35959224 Abstract Title:  Role of Pumpkin Parts as Pharma-Foods: Antihyperglycemic and Antihyperlipidemic Activities of Pumpkin Peel, Flesh, and Seed Powders, in Alloxan-Induced Diabetic Rats. Abstract:  Pumpkin is a well-known vegetable, among the members offamily, due to its importance as pharma food. Keeping in […]

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Astaxanthin ameliorated acetaminophen-induced liver injury.

PMID:  ACS Appl Mater Interfaces. 2022 Sep 12. Epub 2022 Sep 12. PMID: 36094079 Abstract Title:  Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury. Abstract:  Acetaminophen (APAP)-induced liver injury (AILI) is a common liver disease in clinical practice. Only one clinically approved drug,-acetylcysteine (NAC), for the treatment of […]

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DHA and EPA prevent seizure and depression-like behavior.

PMID:  Mol Nutr Food Res. 2022 Sep 13:e2200275. Epub 2022 Sep 13. PMID: 36099650 Abstract Title:  DHA and EPA Prevent Seizure and Depression-Like Behavior by Inhibiting Ferroptosis and Neuroinflammation via Different Mode-of-actions in a Pentylenetetrazole-Induced Kindling Model in Mice. Abstract:  SCOPE: It has been reported that eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have anticonvulsant […]

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