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Anticancer bioactivity of zerumbone on pediatric rhabdomyosarcoma cells.

PMID:  J Cancer Res Clin Oncol. 2022 Aug 5. Epub 2022 Aug 5. PMID: 35931788 Abstract Title:  Anticancer bioactivity of zerumbone on pediatric rhabdomyosarcoma cells. Abstract:  PURPOSE: Natural products are generally regarded as safe and have been shown to mediate anticancer activities against a variety of cell types. Zerumbone is a natural cyclic sesquiterpene derived […]

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Tumor-inhibitory effects of zerumbone against HT-29 human colorectal cancer cells.

PMID:  Int J Toxicol. 2022 Sep-Oct;41(5):402-411. Epub 2022 Jun 19. PMID: 35719111 Abstract Title:  Tumor-Inhibitory Effects of Zerumbone Against HT-29 Human Colorectal Cancer Cells. Abstract:  Colorectal cancer (CRC) is the second cause of cancer-associated death globally. Recently, herbal medicinal products and, in particular, zerumbone have been widely studied and used for cancer treatment as they […]

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Zeaxanthin attenuates OVA-induced allergic asthma.

PMID:  Allergol Immunopathol (Madr). 2022 ;50(5):75-83. Epub 2022 Sep 1. PMID: 36086967 Abstract Title:  Zeaxanthin attenuates OVA-induced allergic asthma in mice by regulating the p38 MAPK/β-catenin signaling pathway. Abstract:  BACKGROUND: Asthma is a heterogeneous and complex chronic airway disease with a high incidence rate, characterized by chronic airway inflammation. Although the anti-inflammatory effect of zeaxanthin […]

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The protective effects of zeaxanthin on amyloid-β peptide 1-42-induced impairment of learning and memory ability.

PMID:  Front Behav Neurosci. 2022 ;16:912896. Epub 2022 Jun 23. PMID: 35813593 Abstract Title:  The Protective Effects of Zeaxanthin on Amyloid-β Peptide 1-42-Induced Impairment of Learning and Memory Ability in Rats. Abstract:  Background and Objectives: Zeaxanthin (ZEA) as one of the biologically active phytochemicals presents a neuroprotective effect. Since ZEA may play its anti-oxidative role […]

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A combined micronutrient dietary supplement should be considered in the overall management of AD.

PMID:  J Alzheimers Dis. 2022 Sep 9. Epub 2022 Sep 9. PMID: 36093704 Abstract Title:  Supplementation With Carotenoids, Omega-3 Fatty Acids, and Vitamin E Has a Positive Effect on the Symptoms and Progression of Alzheimer's Disease. Abstract:  BACKGROUND: Preliminary work by our center has reported behavior and functional benefits in patients with Alzheimer's disease (AD) following […]

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Omega-3 fatty acids for the management of osteoarthritis.

PMID:  Nutrients. 2022 Aug 16 ;14(16). Epub 2022 Aug 16. PMID: 36014868 Abstract Title:  Omega-3 Fatty Acids for the Management of Osteoarthritis: A Narrative Review. Abstract:  Osteoarthritis (OA) is a disease which results in degeneration of cartilage within joints and affects approximately 13.6% of adults over 20 years of age in Canada and the United […]

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Omega-3 fatty Acids for Major Depressive Disorder With High Inflammation.

PMID:  J Clin Psychiatry. 2022 Aug 22 ;83(5). Epub 2022 Aug 22. PMID: 36005883 Abstract Title:  Omega-3 Fatty Acids for Major Depressive Disorder With High Inflammation: A Randomized Dose-Finding Clinical Trial. Abstract:  : This study compared the impact of 3 eicosapentaenoic acid (EPA) doses versus placebo on inflammatory biomarkers and depressive symptoms.: Sixty-one unmedicated adults […]

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Omega-3 showed promising effects on systemic inflammation by reducing CRP levels in COVID-19 patients.

PMID:  J Transl Med. 2022 Sep 5 ;20(1):401. Epub 2022 Sep 5. PMID: 36064554 Abstract Title:  Effect of Omega-3 fatty acids supplementation on serum level of C-reactive protein in patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials. Abstract:  BACKGROUND: Omega-3 may alleviate the severity of coronavirus disease 2019 (COVID-19) by reducing […]

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The beneficial effects of omega-3 polyunsaturated fatty acids on controlling blood pressure.

PMID:  Front Nutr. 2022 ;9:985451. Epub 2022 Aug 18. PMID: 36061895 Abstract Title:  The beneficial effects of omega-3 polyunsaturated fatty acids on controlling blood pressure: An umbrella meta-analysis. Abstract:  Several meta-analyses have revealed that n-3 PUFAs can lower blood pressure, but the findings are conflicting. In this regard, the present umbrella meta-analysis aimed was performed […]

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Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect.

PMID:  Mil Med Res. 2022 05 20 ;9(1):22. Epub 2022 May 20. PMID: 35596191 Abstract Title:  Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect. Abstract:  BACKGROUND: Sepsis involves life-threatening organ dysfunction and is caused by a dysregulated host response to infection. No specific therapies against sepsis have been reported. Celastrol (Cel) is […]

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