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Genistein effects on various human disorders mediated via Nrf2 signaling.

By : on : December 5, 2022 comments : (0)

PMID:  Curr Mol Med. 2022 Nov 28. Epub 2022 Nov 28. PMID: 36443970 Abstract Title:  Genistein Effects on Various Human Disorders Mediated via Nrf2 Signaling. Abstract:  Genistein is a flavonoid, mostly found in soybean extract and is widely used for its antioxidant and anti-inflammatory activities. Genistein can interact with estrogen receptors due to its structural […]

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Trust The Mask Science: “No Statistical Significance”

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By Rosanne Lindsay, Naturopath After years of masking against a perceived viral threat – “the spike protein” – that was later injected into millions of willing people, the answer is always the same:    Trust the Science. The obvious question is always overlooked.  Is the science valid? Does the mask work? The Latest Mask Study […]

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The effectiveness of herbal medicines on cyclic mastalgia.

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PMID:  Rev Bras Ginecol Obstet. 2022 Oct ;44(10):972-985. Epub 2022 Nov 29. PMID: 36446563 Abstract Title:  The Effectiveness of Herbal Medicines on Cyclic Mastalgia: A Systematic Review on Meta-analysis. Abstract:  OBJECTIVE:  Different drugs are used to treat mastalgia, such as danazol and bromocriptine, and both are associated with side effects, due to which most of […]

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Eating Just Over 2 Cups of Grapes May Help Prevent Sunburns and Skin Cancer

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By Study Finds Eating grapes can help stop people from getting sunburn, according to a new study. Scientists found that people who ate two-and-a-quarter cups of grapes every day for two weeks displayed more resistance to damage from ultraviolet light to their skin. The study, supported by the California Table Grape Commission, found natural components, […]

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Shikonin targets to m6A-modified oxidative damage pathway to alleviate benzene-induced testicular injury.

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PMID:  Food Chem Toxicol. 2022 Dec ;170:113496. Epub 2022 Oct 25. PMID: 36306860 Abstract Title:  Shikonin targets to m6A-modified oxidative damage pathway to alleviate benzene-induced testicular injury. Abstract:  Benzene exposure causes reproductive toxicity through oxidative damage. However, the specific mechanisms of benzene-induced testicular damage and the potential therapeutic drugs remain poorly understood. In the present […]

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How To Grow Tomatoes Indoors

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By Amy Allen It’s pretty standard wisdom that there are few things better tasting than homegrown tomatoes! Granted, some people don’t like tomatoes, but for those of us who do, the taste of a fresh tomato from the garden simply cannot compare to store-bought. But what do we do once the garden is done? Perhaps […]

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Shikonin mediates apoptosis through G protein-coupled estrogen receptor of ovarian cancer cells.

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PMID:  Evid Based Complement Alternat Med. 2022 ;2022:6517732. Epub 2022 Oct 5. PMID: 36248433 Abstract Title:  Shikonin Mediates Apoptosis through G Protein-Coupled Estrogen Receptor of Ovarian Cancer Cells. Abstract:  This study was intended to establish the predictive target of Shikonin (SK) against ovarian cancer using network pharmacology and to clarify the potential mechanism of SK […]

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CDC, HHS Offer $1 Million for Research to Predict Vaccine “Misinformation Trends”

By : on : December 5, 2022 comments : (0)

By Michael Nevradakis | The Defender This article was originally published by The Defender — Children’s Health Defense’s News & Views Website. Two federal public health agencies will provide $1 million in grant funding to develop “a “public health tool” to predict vaccine “misinformation trends.” According to the grants.gov website, the U.S. Department of Health […]

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Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells.

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PMID:  Life Sci. 2022 Dec 1 ;310:121077. Epub 2022 Oct 13. PMID: 36244412 Abstract Title:  Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis. Abstract:  AIMS: PDK1 is one of the key enzymes in the glucose metabolism pathway, which is abnormally high expressed in […]

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Nobiletin therapy could prevent colon cancer progression by inhibiting Akt signaling and angiogenesis.

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PMID:  Naunyn Schmiedebergs Arch Pharmacol. 2022 Dec 1. Epub 2022 Dec 1. PMID: 36454256 Abstract Title:  Nobiletin is capable of regulating certain anti-cancer pathways in a colon cancer cell line. Abstract:  Natural remedies have the potential to improve conventional cancer therapies and enhance patient outcomes. Citrus polymethoxyflavone nobiletin has been demonstrated to have anticancer effects […]

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